アブストラクト（2巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： The Effect of Acetylcholine on Lingual Circulation in Dogs
Subtitle　： Short Communication
Authors　： Hidehiko Matsukawa1, Kazuto Takahashi2, Haruo Ito1
Authors（kana）　：
Organization　： 1Department of Pharmacology, Kanagawa Dental College, 2Department of Oral Anatomy, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 2
Number　： 1
Page　： 87-88
Year/Month　： 1974 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： Hilton and Lewis (1958) observed that submental vasodilatation induced by the stimulation of chordolingual nerve was not blocked by atropine. He further suggested that kinin substances were a ciculatory hormone which regulated lingual circulation. We have re-evaluated the lingual circulation and its response to Acetylcholine (Ach) using the following method. A group of mongrel dogs of both sexes, weighing 10-15 kg each, were anesthetized with pentobarbital, 25 mg/kg, intravenosly. A catheter was passed into the femoral artery, and connected to a "Y" shaped catheter which was then inserted into both common carotid arteries. The systemic blood flow rate of femoral artery was measured by an electromagnetic flow probe and a squarewave electromagnetic flowmeter (Nihon Koden MF-2). The femoral arterial blood pressure was measured by a pressure tranceducer (Nihon Koden MP-4T). The lingual capillary flow rate was measured by using a double themocouple.
Practice　： Dentistry
Keywords　： Capillary (blood) flow, Vasoactive factor, Kinin, Ach, Atropine, Phenoxybenzamine, DCI, Anginin, Lingual circulation