アブストラクト（22巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Re-Evaluation of the Biocompatibility of New Ceramics, Hydroxylapatite Titanium, and Silica, Used in Chromatographic Applications
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : BIOMATERIAL
Authors　： Katsuhiro Nishiyama, Mikio Miyama, Osamu Irie, Takashi Osawa, Nobuyoshi Ishi, Nobuaki Arai, Toshio Kawase, Shigeru Saito
Authors（kana）　：
Organization　： Department of Oral Biochemistry, Kanagawa dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 22
Number　： 2
Page　： 139-149
Year/Month　： 1994 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Introduction] Interest in generating new materials for use as permanent hard tissue implants has grown considerably in recent years. The bioceramic which Hench developed contains SiO2, Na2O, CaO, and P2O5, and has a reactive surface which forms a chemical bond with bone. Implants of sintered calcium phosphate become within a few months an intrinsic part of the bone in which they have been implanted. Hydroxylapatite (HA)5 and tricalcium phosphate (β-TCP) are two of the principal types of calcium phosphate ceramics used for bone repair in periodontal defects and in some cases in orthopedic and maxillofacial surgery. Titanium is widely regarded as a highly biocompatible material. Specifically, when the local tissue interaction between titanium and the host is analyzed, a very favorable histological assessment emerges. Albretsson et al showed that bone tissue and titanium are separated only by a very thin, noncalcified tissue layer of approximately 20 nm thick containing, primary, chondroitin sulfate and glycoproteins.
Practice　： Dentistry
Keywords　： Biocompatibility, Hydroxylapatite, Protein, Nucleotides, ESI, Maspectrometry