アブストラクト（25巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Trial Study of a Rapid and Simplified Analytical Method of 99mTc-labeled Phosphonate using Mini-columns
Subtitle　： SHORT COMMUNICATION
Authors　： Hiromi Wakao, Yayoi Okamoto, Shigeru Satori, Takuya Kanazawa, Isamu Kashima
Authors（kana）　：
Organization　： Department of Radiology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 25
Number　： 1
Page　： 31-33
Year/Month　： 1997 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] 99mTC-labeled phosphonate compounds were analyzed using a mini-column which was an anion-exchange typed cartridge. As a result, free 99mTc was eluted by neutral solution. Some parts of the 99mTc-labeled phosphonates were eluted by alkaline solution. The remaining parts were not from the mini-column. At that time, it was possible to analyze free 99mTc and 99mTc labeled phosphonates in each prepared solution. Moreover, 99mTc-MDP was intravenously injected in rabbits to examine the stability of 99mTc-MDP in the blood. The radioactivity in the alkaline solution fraction decreased gradually, while that in the column fraction increased. Thus, this simple and quick mini-column method was very useful for analysis.
Practice　： Dentistry
Keywords　： Mini-column, 99mTc-MDP, 99mTc-laheled phosphonate, Chromatography