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アブストラクト(28巻1号:The Bulletin of Kanagawa Dental College)
English
Title : | Stretch-sensing mechanisms uniquely expressed in osteocytes |
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Subtitle : | Selective Proceedings of 34th General Meeting of Kanagawa Odontological Society, 1999 |
Authors : | Yuko Mikuni-Takagaki*1, Miho Furue*1, Akira Kawata*2, Tosio Kawase*2, Kennichi Sasaguri*3, Takao Kubota*3, Sadao Sato*3 |
Authors(kana) : | |
Organization : | *1Department of Oral Biochemistry, Kanagawa Dental College, *2Department of Medical Bioengineering, Kanagawa Dental College, *3Department of Orthodontics, Kanagawa Dental College |
Journal : | The Bulletin of Kanagawa Dental College |
Volume : | 28 |
Number : | 1 |
Page : | 77-80 |
Year/Month : | 2000 / 3 |
Article : | Report |
Publisher : | Kanagawa Odontological Society |
Abstract : | [Abstract] Unique combination of multiple ion channels is functioning in osteocytes to receive and process mechanical stimuli. We identified 1) epithelial-like Na channel (ENaC) and 2) a splice variant of the functional subunit α1C of the voltage dependent L-type channel in osteocytic calvarial cell population. Differentiation of osteocytes that accompanies loss of proliferation and development of extensive cell processes are essential to their unique mechanical responses. |
Practice : | Dentistry |
Keywords : | Osteocytes, Ion channels, Stretch, Mechanotransduction, Anabolic |