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アブストラクト（37巻2号：The Bulletin of Kanagawa Dental College）
English
| Title ： | Mast Cell Distribution and TLR Expression in Rat Tongue Epithelia |
|---|---|
| Subtitle ： | ORIGINAL ARTICLES |
| Authors ： | Tomoko Sugiyama*1, Yoshinori Jinbu*1, Yuri Obi*1, Mikio Kusama*1, Toshio Demitsu*2, Keiichi Tsukinoki*3 |
| Authors（kana） ： | |
| Organization ： | *1Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, *2Department of Dermatology, Saitama Medical Center, Jichi Medical University, *3Division of Pathology, Department of Oral Diagnostic Science, Kanagawa Dental College |
| Journal ： | The Bulletin of Kanagawa Dental College |
| Volume ： | 37 |
| Number ： | 2 |
| Page ： | 101-103 |
| Year/Month ： | 2009 / 9 |
| Article ： | Original article |
| Publisher ： | Kanagawa Odontological Society |
| Abstract ： | [Abstract] Mast cells play a critical role in host defense against bacterial infection, as well as in immediate-type allergic reactions. We investigated the distribution of mast cells and expression of mast cell Toll-like receptors (TLR) in rat tongue epithelia. Mast cells were preferentially distributed in the muscle layer rather than in the lamina propria. Expression of TLR-4 was observed in mast cells in the lamina propria, and strong positive staining was detected in mast cells in the muscle layer. No positive staining for TLR-2 was observed in rat tongue epithelia. |
| Practice ： | Dentistry |
| Keywords ： | Mast cell, Toll-like receptor 4, Toll-like receptor 2, Tongue, Rat |
