アブストラクト（5巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Immune Response After Treatment of 6MP and Azathioprine
Subtitle　： ORIGINAL ARTICLES
Authors　： Koichi Kato*, Sakuji Fukushima*, Saburo Kato*, Eriko Soma*, Tsuneo Kuramochi**
Authors（kana）　：
Organization　： *Department of Bacteriology, Kanagawa Dental College, **Kidney Center, Tokyo Women's Medical College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 5
Number　： 1
Page　： 53-59
Year/Month　： 1977 / 3
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] In our experiments, immune response of rabbits treated with 6MP or azathioprine has been studied with the production of precipitin antibody and skin reactions. Treating rabbits with 6MP or azathioprine, the production of the specific antibody, was inhibited during the first stage of our experiment. At this stage, allergic reaction was difficult to develop even after an allergic-reaction-inducing injection. However, antibody detecting in the blood stream, erythema (redness, conspicuous edema and swelling) occurred at the injected sites following the provoking injection of the antigen. The antibody of the rabbits treated with 6MP and azathioprine disappeared from the blood stream faster than that of untreated control animals.
Practice　： Dentistry
Keywords　： immunosuppressive, Allergic reaction, Immune response