アブストラクト（10巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Microtubules and Actin Filaments as Cytoskeleton of the Ameloblast in the Rat Incisor
Subtitle　： ORIGINAL ARTICLES
Authors　： Sumio Nishikawa
Authors（kana）　：
Organization　： Department of Oral Histology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 10
Number　： 2
Page　： 95-115
Year/Month　： 1982 / 9
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Microtubules and actin filaments in the ameloblast of a rat incisor were morphologically investigated by quantitative analysis, serial sectioning method, colcemid treatment for disruption of microtubules, and heavy-meromyosin covering method for actin filaments. During differentiation of the ameloblast, the total number of microtubules increased. In the secretory stage, microtubules were abundant in the distal part of the cell excepting the distal part of the Tomes' process, whereas they were relatively few in the proximal part of the cell. Two different types of microtubules were present in the ameloblast. One was single-typed microtubules, and the other bundle-typed microtubules associated with filaments or a sheet of filaments. Bundle-typed microtubules were abundant between the Golgi apparatus and the Tomes' process. And some of the bundle-typed microtubules were observed to be continuous in part to the single-typed microtubules in serial sections of the ameloblast. Colcemid-treated cells revealed that the maintenance of a secretory pathway of the ameloblasts depended upon the microtubules. Actin filaments mainly distributed lengthwise in the cell periphery, were extensively detected in the Tomes' process. Some of them were related to the microtubules. It is suggested that microtubules forming a loose network play a key role in transportation of secretion granules with the aid of actin filaments in the secretory ameloblast.
Practice　： Dentistry
Keywords　： Microtubules, Actin Filaments, Ameloblast, Secretion