アブストラクト（11巻1/2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Effects on Dentinogenesis in the Incisor by Disconnection of the Common Carotid Artery or by Lesion of the Caudate Nucleus in Rats
Subtitle　： ORIGINAL ARTICLES
Authors　： Osamu Ashida, Hironori Kitamura*
Authors（kana）　：
Organization　： Department of Pedodontics, Kanagawa Dental College, *Department of Oral Histology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 11
Number　： 1/2
Page　： 29-36
Year/Month　： 1983 / 3
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] As to 9 albino rats of Wistar strain with the common carotid artery ligated and 15 rats with electrolytic lesion in the caudate nucleus, the dental pulp and the brain lesion were examined histologically and the relation of the caudate nucleus lesion to the dentinogenesis was discussed. The mandibular incisors in the animals from the experimental and control groups were marked with Pb-EDTA for daily deposition of dentin matrix. Ligation of the common carotid artery exerted a suppressive influence on the dentinogenesis, but it also brought about vacuole degeneration in the caudate nucleus. The electrolytic lesion in the caudate nucleus brought about marked fluctuations in rhythmicities of daily dentin formation in the incisor. Suppressive and accelerative influences on the dentinogenesis appeared intermingled in the lead lines indicating the daily dentin deposition after operation. It is reported that dentin formation was accelerated in some animals with the caudate nucleus lesion. This finding agrees with a theory in the textbook indicating a suppressive function of the caudate nucleus. In some other animals with the caudate nucleus lesion, a remarkable reduction in amount of daily dentin formation was found. The result of the present study suggests that the cerebrum nucleus together with the hippocampus could be closely related to regulation of dentinogenesis which is involved with memory.
Practice　： Dentistry
Keywords　： Dentinogenesis, Rat Incisor, Caudate Nucleus Lesion