アブストラクト（13巻1/2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Effect of Orthodontic Forces on the Enzyme Activities in Rabbit Alveolar Bones
Subtitle　： ORIGINAL ARTICLES
Authors　： Teruaki Kamei, Sadao Sato, Yasujiro Sasaki, Tomoko Oosawa, Yoshii Suzuki
Authors（kana）　：
Organization　： Department of Orthodontics, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 13
Number　： 1/2
Page　： 47-55
Year/Month　： 1985 / 3
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] The activities of enzymes with regard to remodeling processes of the periodontium were studied after orthodontic tooth movement for four days in alveolar bone using rabbits as experimental animals. Fifty male Japanese white rabbits, consisting of 25 young and adult animals respectively, wore the specially-designed orthodontic appliance on their upper incisors except control animals who did not receive any orthodontic force. The orthodontic forces were ranged about 5, 20, 50 and 100g expanding stimulation. After tooth movement, the alveolar bones were removed, homogenized and centrifuged. Whole homogenates were assayed for acid phosphatase, alkaline phosphatase, hyaluronidase, cathepsin B, cathepsin D and collagenase. The enzymal activities of alveolar bones of young and adult animals were remarkably altered associated with orthodontic force. The acid phosphatase, alkaline phosphatase and hyaluronidase in experimental animals were obviously affected by the application of light orthodontic forces, while the acid proteases (cathepsins) were activated by relatively heavy orthodontic stimulations. Those activities of the enzymes in young animals were usually higher than those in adult animals, indicating high remodeling activity in young animals. The observations of enzymatic changes influenced by orthodontic forces clearly indicated that there were different optimum forces which induced the maximum activities of the enzymes for young or adult animals.
Practice　： Dentistry
Keywords　： Enzyme Activity, Alveolar Bone, Orthodontic Forces, Rabbit