アブストラクト(14巻1/2号:The Bulletin of Kanagawa Dental College)

The Bulletin of Kanagawa Dental College

English

Title : Development of the Halved Tooth Bud Grafts : A Study on the Mechanism of Duplicated or Supernumerary Teeth Formation
Subtitle : ORIGINAL ARTICLES
Authors : Hironori Kitamura, Masayoshi Koizumi
Authors(kana) :
Organization : Department of Oral Histology, Kanagawa Dental College
Journal : The Bulletin of Kanagawa Dental College
Volume : 14
Number : 1/2
Page : 37-43
Year/Month : 1986 / 3
Article : Original article
Publisher : Kanagawa Odontological Society
Abstract : [Abstract] Each of the two halves of a bell-shaped molar bud with no calcification, mandibular first or second molar, from a 4-day-old hamster was grafted in a subcutaneous space behind the ear or in the pouch of a young hamster of the same strain. After 30 days of grafting the grafts were harvested, fixed and histologically sectioned. The halved or larger segment formed an elongated root, but it tended to remain a slit in the cervix or in the root closer to the cervix. This slit formation indicates the wounded part was not entirely closed. The malformed crown and root suggest that something could have gone wrong with the severed enamel epithelia after extension by proliferation. However, five good or fairly good-shaped teeth have been developed. The halved m2 buds formed good-shaped cusps similar to the normal pattern, whereas the halved m1 buds brought about cusps a little different from the normal pattern. This means that the younger the halved buds were, the better shaped duplicate teeth developed. A smaller segment developed a miniature tooth with a single cusp, while a larger segment formed a two-cusp tooth with an apposed cusp.
Practice : Dentistry
Keywords : Tooth Bud, Experimental Embryology, Graft, Hamster