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アブストラクト(22巻1号:The Bulletin of Kanagawa Dental College)
English
Title : | Immunohistochemical Study on γ-Carboxyglutamic Acid Containing Protein (Osteocalcin, BGP) in Human Dentin and Alveolar Bone |
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Subtitle : | ORIGINAL ARTICLES |
Authors : | Yoshinori Jinbu1, Yoshihisa Watanabe2, Yukari Yamaguchi2, Tsuneo Takahashi3, Yoko Akasaka4, Isamu Kashima1 |
Authors(kana) : | |
Organization : | 1Departments of Oral and Maxillofacial Radiology, Kanagawa Dental College, 2Departments of Oral Pathology, Kanagawa Dental College, 3Departments of Oral Anatomy, Kanagawa Dental College, 4Department of Dentistry and Oral Surgery, Jichi Medical School |
Journal : | The Bulletin of Kanagawa Dental College |
Volume : | 22 |
Number : | 1 |
Page : | 3-7 |
Year/Month : | 1994 / 3 |
Article : | Original article |
Publisher : | Kanagawa Odontological Society |
Abstract : | [Abstract] γ-Carboxyglutamic acid containing protein (osteocalcin, bone Gla protein ; BGP) is considered to play an important role in the mineralization process. Immunohistochemical localization of BGP was investigated in human teeth and in alveolar bone. Positive reaction was found in the intratubular matrix of dentin, in the secondary dentin, in some of odontoblasts and their processes, also in parts of the bone matrix and in the cement. However, no reaction was observed in predentin. The results support the concept that BGP is produced by odontoblasts and deposited on the mineralized dentin, and may control the mineralization process of dentin as well as that of bone. |
Practice : | Dentistry |
Keywords : | γ-Carboxyglutamic Acid Containing Protein, Osteocalcin, Immunohistochemistry, Human Dentin, Human Alveolar Bone |