アブストラクト（26巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Application of Resin Using Fluoride for the Prevention of Dental Caries
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : Bioadaptives of Dental Materials
Authors　： Yukio Hirata, Hirohisa Arakawa, Yoshikazu Iizuka
Authors（kana）　：
Organization　： Department of Dental Health and Public Health
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 26
Number　： 2
Page　： 98-102
Year/Month　： 1998 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] One of the most important factors for the prevention of dental caries is to maintain a constant level of fluoride concentration in saliva. Two studies on the delivery system of a certain level of fluoride using resin in a slow release system with the aim of the prevention of dental caries were introduced: [I] Study with the Intraoral Fluoride Releasing Device (IFRD) developed by the American Southern Research Institute was carried out. The configuration of IFRD is a tablet type that is constructed by matrix (MMA:HEMA=50:50, NaF) and membrane (MMA:HEMA=70:30). The principle of releasing fluoride through IFRD utilizes the difference of hydrophilicity between the matrix and the membrane. A solvent passes through the membrane, infiltrates the matrix and dissolves NaF, and then NaF solution is released slowly from IFRD to outside the membrane. The release rate of NaF is determined by the surface area and thickness of the membrane. In application of the fluoride-releasing device (IFRD) on the molar-fissures of rats, dental caries were significantly reduced (more than 90%) compared to the placebo group. [II] Study on the possibility of denture base resin as a fluoride supplying vehicle was carried out. The possibility of whether or not the vehicle of resin takes in fluoride from external solutions and releases fluoride again to external solutions was examined. A resin cube as denture base resin made according to routine procedure was divided into three groups, and soaked at room temperature in solutions of fluoride concentration of 500ppm, 1000ppm, 1000ppm for 13 hours. Then each cube was soaked in distilled water with successively changing water for 60 minutes, 60 minutes, 90 minutes and 120 minutes, and the fluoride concentration in the distilled water was measured. As a result, the release of fluoride was recognized even after a lapse of three and a half hours. Therefore, it was suggested that resin might be an effective supplying vehicle of fluoride for dental caries prevention.
Practice　： Dentistry
Keywords　： Resin, IFRD, Slow release system. The prevention of dental caries