アブストラクト（27巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Detection of Activated MMPs in the Early Development of Rat Submandibular Glands
Subtitle　： Selective Proceedings of 33rd General Meeting of Kanagawa Odontological Society, 1998
Authors　： Yumi Ito, Kazuyoshi Sato, Satoru Ozono
Authors（kana）　：
Organization　： Department of Oral Pathology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 27
Number　： 1
Page　： 53-54
Year/Month　： 1999 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [ABSTRACT] We have demonstrated the expression of the activated Matrix metalloproteases (MMP) in the early development of submandibular gland (SMG) in rats using a conbination of film in situ hybridization (FIZ) and immunohistochemical techniques. FIZ was recently developed which was detected MMPs directly on sections. The expression of MMPs was shown mainly in ductal cells, which used FIZ and immunohistochemical techniques, in early development of SMGs in rat. These data suggest that MMPs is identified in the normal SMG of rats and located only in the duct system, and that activated form may play an important role in cell proliferation and growth of the glands.
Practice　： Dentistry
Keywords　： matrix metalloproteases, film in situ hybridization, postnetal development, submandibular glands