アブストラクト（29巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Salivary Fluoride Levels after Spraying with 500 or 1,000 ppmF Fluoride Solution
Subtitle　： ORIGINAL ARTICLES
Authors　： Kazunari Kimoto, Shinji Toda, Wenqun Song, Kazumi Kuroha, Shizuho Usui, Kazuaki Kawamura, Yukio Hirata, Hirohisa Arakawa
Authors（kana）　：
Organization　： Department of Dental Health & Public Health, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 29
Number　： 2
Page　： 75-79
Year/Month　： 2001 / 9
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] RENOVIGO(R), as a self-care vehicle for caries prevention, was developed to supply a proper amount of fluoride leading to remineralization in the oral environment through a spray application of 100 ppmF solution (one application corresponds to a supply of 3.3μg F). However, the salivary fluoride level after the ordinary use of RENOVIGO(R) was too low to enhance remineralization. Therefore, it is necessary to apply the spray several times a day using 10-15 sprays per application of RENOVIGO(R), and/or to increase the fluoride concentration of the solution to 500-1,000 ppmF. In the present study, after a five-spray-application of 500 or 1,000 ppmF solution (containing approximately 0.08 or 0.16mg F respectively), the salivary flow rates and the fluoride concentrations of unstimulated whole saliva samples collected at the baseline, 5, 10, 20, 30, 60, 90 and 120 min after were measured. The mean fluoride concentration in the baseline saliva was 0.02+-0.01 ppmF. Five minutes after the application of 500 or 1,000 ppmF fluoride solution, the fluoride concentrations in the saliva had increased to 1.30+-1.34 and 2.89+-2.51 ppmF respectively. The fluoride concentrations declined up to 30 and 60 min after spraying in both groups, significantly different from the baseline levels. The salivary fluoride levels decreased slowly thereafter. It is believed that a proper amount of fluoride leads to the enhancing of remineralization and a decrease in the cariogenicity of dental plaque in accordance with fluoride retention in the oral environment. These results suggest that the fluoride concentration of RENOVIGO(R) (100 ppmF solution) should be elevated to 500-1,000 ppmF to enhance caries preventive effects.
Practice　： Dentistry
Keywords　： Salivary fluoride, Fluoride solution, Spray application