アブストラクト（31巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Twenty-four Hours Fluoride Intake and Excretion of Fluoride in Urine in Japanese Adults
Subtitle　： ORIGINAL ARTICLES
Authors　： Mariko Komiyama, Wenqun Song, Shinji Toda
Authors（kana）　：
Organization　： Department of Dental Health and Public Health, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 31
Number　： 1
Page　： 17-25
Year/Month　： 2003 / 3
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： Only a few studies evaluated the relationship between 24-hour fluoride intake from cooked food and drink and excretion of fluoride in urine. Also, it was of interest whether an excessive intake of fluoride would occur or not when Japanese people were exposed to fluoridated water at 1 ppm. We measured the fluoride intake and excretion in six adults on two different days under two different conditions: tap water used for cooking and drinking being either 0.062 ppm (non-fluoridated water) or 1.0 ppm (fluoridated water). The latter fluoride concentration in tap water has been recommended for the optimum prevention of dental caries. The mean of total fluoride ingested in 24 hours was 1,173 μg with non-fluoridated water: 136 μg from food and 1,037 μg from drink, and 2,213 μg with fluoridated water: 686 μg from food and 1,526 μg from drink. The dietary intake measured 18.2 and 34.6 μg F/kg body weight. None of the subjects exceeded the 50 μg F/kg body weight, which is recommended as the adequate daily intake of fluoride, while 100 μg F/kg body is regarded as tolerable upper limit. On the average, 78% or 61% of the total ingested fluoride was excreted in urine in the presence or absence of added fluoride. Of note, the average concentration of salivary fluoride at 30 minutes after dinner was 0.03 ppm and 0.01 ppm, respectively, supporting the notion that prepared food including drinks with fluoridated water is a useful vehicle to enhance remineralization of incipient carious lesion. These results provide basis for the safety and effectiveness of implementation of water fluoridation in Japan.
Practice　： Dentistry
Keywords　： Fluoride intake, Excretion of fluoride in urine, Water fluoridation, Fluoride concentration in saliva