アブストラクト（32巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Immunoelectron Microscopic Examination of GABA- and Glycine-immunoreactive Axon Terminals on Motoneurons in Rat Trigeminal Motor Nucleus
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : Research Topics from the Research Center of Advanced Technology for Craniomandibular Function in Kanagawa Dental College
Authors　： Osamu Takahashi
Authors（kana）　：
Organization　： Department of Oral Histology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 32
Number　： 1
Page　： 57-61
Year/Month　： 2004 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Introduction] Projections from the cerebral cortex, basal ganglia, and amygdala to the trigeminal motor nucleus (Vm) are the main constituents through which the masticatory motoneurons are influenced. Neuronal signals from pyramidal cells in layer V of the sensorimotor and premotor cerebral cortical regions are usually mediated to Vm via interneurons in the lower brain stem, although some cerebral cortical fibers have been shown to end directly within the trigeminal motor nucleus in macaque monkeys and man. The interneurons that send their axons directly to Vm are distributed most frequently in the lateral part of the pontine and medullary reticular formation, including the gigantocellular reticular nucleus and medullary raphe nuclei. In the rat, major output structures of the basal ganglia, the entopeduncular nucleus and the substantia nigra pars reticulata (including the substantia nigra pars lateralis), have been found to send projection fibers to the lower brain stem, which run through the lateral part of the pontine and medullary reticular formation, bilaterally with ipsilateral predominance. The cells of origin of these descending fibers are located in the rostroventral regions of the entopeduncular nucleus, substantia nigra pars lateralis, lateral portions of the substantia nigra pars reticulata ; these regions appear to be innervated by the orofacial fields of the sensorimotor and premotor cerebral cortices via the ventrolateral parts of the caudateputamen.
Practice　： Dentistry
Keywords　： Trigeminal motor nucleus, GABA, Glycine, Receptor, Rat