アブストラクト（32巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Telomere Length, Telomerase Activity and Expression of Human Telomerase Reverse Transcriptase (hTERT) mRNA in Head and Neck Squamous Cell Carcinoma
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : Research Topics from the Research Center of Advanced Technology for Craniomandibular Function in Kanagawa Dental College
Authors　： Yuuichi Sasakura*, Yoshiko Miyoshi**, Yoshihisa Watanabe**
Authors（kana）　：
Organization　： *Department of Maxillofacial Surgery, Kanagawa Dental College, **Department of Oral Pathology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 32
Number　： 1
Page　： 69-73
Year/Month　： 2004 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Carcinoma immortalized cells in the oral and maxillofacial region cause oral dysfunctions, i.e. ; in mastication, occlusion, swallowing, pronunciation, etc. It has been postulated that telomerase reactivation may control telomeric restriction fragment length (TRFL), telomeric stabilization senescence and cell immortalization thereby inducing carcinoma. This short review attends closely to the diagnostic capability of telomerase and TRFL. Also presented in this study is an examination of the relationship between telomere length, telomerase activity and the expression of human telomerase reverse transcriptase mRNA in head and neck squamous cell carcinoma.
Practice　： Dentistry
Keywords　：