アブストラクト（32巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Neurons expressing glutamic acid decarboxylase mRNA in the supratrigeminal nucleus of rats
Subtitle　： Selective Proceedings of 38th General Meeting of Kanagawa Odontological Society, 2003
Authors　： Akira Kawata, Hiroyuki Hayashi, Hideko Tsuzuki, Kazuyoshi Higashi, Koji Takahashi, Osamu Takahashi
Authors（kana）　：
Organization　： Department of oral Histology, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 32
Number　： 2
Page　： 130-132
Year/Month　： 2004 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： The supratrigeminal nucleus (sV) contains commissural gamma aminobutyric acid (GABA)ergic neurons that send axons to the motor trigeminal nucleus (Vm). In the present study we synthesized digoxigenin-labeled cRNA probes to two isoforms of glutamic acid decarboxylase (GAD), now termed GAD65 and GAD67, for in situ hybridization. In the sV, expressions of two types of GAD mRNAs were observed. There was no difference in expression on cell somata and neuronal distribution between GAD65 and GAD67. These results suggests that two types of GAD probes may be useful for quantitative and qualitative studies of GAD65 and GAD67 gene expression in the postnatal development of rat brain.
Practice　： Dentistry
Keywords　： GAD65, GAD67, Supratrigeminal nucleus, In situ hybridization