アブストラクト（33巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Bone Regeneration : Effect of Basic Fibroblast Growth Factor / Estrogen Combinations on Bone Formation in Rat B one Marrow Stromal Cells
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : Current Topics of Tissue Engineering in Dentistry
Authors　： Satoru Ozono1), Yukihiko Kinoshita1), Hideyuki Negishi1),2), Toshio Kawase1),2)
Authors（kana）　：
Organization　： 1)Institute for Frontier Oral Science, Kanagawa Dental College, 2)Departments of Dental Bioengineering, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 33
Number　： 1
Page　： 25-30
Year/Month　： 2005 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Engineering new bone tissue using cells and a synthetic extracellular matrix (scaffolding) represents an alternative strategy for the regeneration of mineralized tissues compared with the transplantation of bone (autografts or allografts). In particular, the tissue engineering of bone by combining bone-marrow stromal cells (BMSCs) with a porous β-TCP scaffold is considered a promising technique. Here, we summarize the recent evidence of basic fibroblast growth factor and estradiol-17β, in regard to the functional significance of supplement addition in the bone formation of BMSCs.
Practice　： Dentistry
Keywords　： Rat bone-marrow stromal cells, Osteogenesis, bFGF, Estrogen, Bone formation