アブストラクト（33巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Molecular Mechanisms of Periodontal Development, and Its Prospect of Regenerative Medicine for Periodontium
Subtitle　： BKDC CLINICAL AND RESEARCH TOPICS : Current Topics of Tissue Engineering in Dentistry
Authors　： Masahiro Saito1),4),5), Akira Tsunoda1), Takamasa Yokoi1),6), Shintaro Hattori2), Takanori Tsubakimoto1), Eisaku Nishida1),6), Kazutaka Kousaka1), Minoru Toyoda2), Sadao Sato3), Toshihide Noguchi6), Toshio Teranaka1),4),5)
Authors（kana）　：
Organization　： 1)Department of Operative Dentistry and Endodontics, Kanagawa Dental College, 2)Department of Prostodontics, Kanagawa Dental College, 3)Department of Orthodontics, Kanagawa Dental College, 4)Research Center of Advanced Technology for Craniomandibular Function, Kanagawa Dental College, 5)Institute for Frontier Oral Science, Kanagawa Dental College, 6)Department of Periodontology, School of Dentistry, Aichi-Gakuin University
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 33
Number　： 1
Page　： 31-35
Year/Month　： 2005 / 3
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Periodontitis is a chronic inflammatory disease which destroys the periodontium including alveolar bone, cementum and periodontal ligament, and which simultaneously brings about the abolition of the occlusion system. In periodontal therapy, the diseased area is removed as a symptomatic treatment and regenerative therapy is performed using artificial material. However, there are limitations to complete reorganization. For the establishment of a more positive treatment that includes total reconstruction of the physiological occlusion system, development of cell therapy using stem cell or progenitors that possessed differentiation potential is essential. This strategy should be based on the embryological processes of the periodontium. Establishment of the stem / progenitor cell line presented in the periodontium would provide us the possibility of not only the development of a new periodontal therapy utilizing tissue engineering, but would also provide us with the means of developing an implant that includes a periodontal ligament.
Practice　： Dentistry
Keywords　： Development, Periodontium, Regeneration, Progenitor