アブストラクト（34巻1号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Microvascular Changes and Bone Formation after Autograft - Differences in Regeneration Processes between Cancellous and Cortical Bone Graft -
Subtitle　： ORIGINAL ARTICLES
Authors　： Masato Matsuo
Authors（kana）　：
Organization　： Tissue Engineering Division, Institute for Frontier Oral Science, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 34
Number　： 1
Page　： 9-15
Year/Month　： 2006 / 3
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Bone regeneration therapy is believed to be effective in recovering bone defects in the dental field. Various kinds of bone regeneration therapies have been used in an attempt to reconstruct the jawbone. Autograft has proved to be one of the most efficient ways to reconstruct the jawbone in clinical cases. In this study, both mandibural tooth sockets of beagle dogs were used. After 14 days and 30 days post operation, the tooth sockets were filled with bone grafts, which were divided into cortical bone, and cancellous bone grafts. As a control a no-bone graft was prepared. Microvascular resin cast is a method of injecting low-viscosity synthetic resin into the blood vessels. A clear, three-dimensional image can be observed through the complete infusion of a synthetic resin up to the capillaries. When this method is used, only bone, teeth and a vascular cast remain and it is possible to observe the relationship between the three. This research concerns an observation of the relationship of the vascular network and alveolar bone using a scanning electronic microscope (SEM). The results of this study indicated that cancellous bone contains many blood vessels with growth factors. Cortical bone works as a scaffold. Both of these interactions greatly enhance bone regeneration. In the future, various examinations of the combination of a factor and a scaffold will be needed.
Practice　： Dentistry
Keywords　： Microcirculation, Autograft, Resin cast