アブストラクト（35巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Restraining of ovariectomized rat deteriorate quality and strength of Bone
Subtitle　： Selective Proceedings of 41st General Meeting of Kanagawa Odontological Society, 2006
Authors　： Kazuaki Miyagawa1), Takami Furuhama1), Yumi Ito2), Yuusuke Kozai3), Ryota Kawamata3), Isamu Kashima3), Yuko Mikuni-Takagaki1)
Authors（kana）　：
Organization　： 1)Department of Functional Biology y, Kanagawa Detal College, 2)Yokohama Training Center, Kanagawa Dental College, 3)Department of Maxillofacial Diagnostic Science, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 35
Number　： 2
Page　： 193-195
Year/Month　： 2007 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract]Lack of estrogen after menopause and reduced physical activity are the important factors of pathogenesis of osteoporosis in the elderly women. We have compared contribution of estrogen and the activity quantitatively. Experimental rats in cages of limited space were restricted their walking. Four groups are comprised of Sham-Control, Sham-Restrained, OVX, and OVX-Restrained rats. Animals were sacrificed 15 weeks later, and femurs and tibiae were examined for the morphological appreciation. OVX-Restrained rat group experienced the worst loss of bone structure as well as the deteriorated bone quality and strength.
Practice　： Dentistry
Keywords　： osteoporosis, ovariectomy, immobilization, bone quality, bone strength