アブストラクト(37巻2号:The Bulletin of Kanagawa Dental College)

The Bulletin of Kanagawa Dental College

English

Title : An Analysis Study on the Accumulation of Toxic Metals in Patients with Suspected Metal Allergy
Subtitle : Selective Proceedings of 43rd General Meeting of Kanagawa Odontological Society, 2008
Authors : Tomofumi Sawada*1,*3, Migiwa Higuchi*1, Tomoji Sawada*1,*3, Shusaku Okada*2,*3, Tota Shimizu*1,*3, Toshio Teranaka*2, Minoru Toyoda*1
Authors(kana) :
Organization : *1Division of Removal Prosthetics, Department of Oral and Maxillofacial Rehabilitation, *2Divison of Restorative Dentistry, Department of Oral Medicine, *3Dental allergy clinic, Kanagawa Dental College
Journal : The Bulletin of Kanagawa Dental College
Volume : 37
Number : 2
Page : 155-157
Year/Month : 2009 / 9
Article : Report
Publisher : Kanagawa Odontological Society
Abstract : [ABSTRACT] The accumulation of toxic metals can cause various health disorders and may accelerate ageing in patients with suspected metal allergy. In this study, we performed a patch test and hair mineral analysis on 50 patients who visited the Dental Allergy Clinic of Kanagawa Dental College between April 2001 and December 2007. The patch test was conducted using 19 dental metals and the skin reaction was evaluated at 2, 3, and 7 days. In hair mineral analysis, scalp hair samples were collected, and the mineral concentrations were measured with inductively coupled plasma mass spectrometry (ICP-MS). In the patch test, positive reactions with Ni, Pd, Pt, Sn, Co, Cr, Au, Zn, Hg, and Mn were observed in a high number of patients. The results of the hair mineral analysis, more than 70% of the patients, the accumulation levels of Cd, Hg, Al, Pb, and As were higher than the moderate range. In addition, the Hg accumulation was found to increase with ageing. In conclusion, we confirmed that patients with metal allergy showed accumulation of toxic metals. [INTRODUCTION] Recently, the concept of anti-ageing has spread worldwide because of the increasing interest in health maintenance. Mineral balance is vital for the maintenance of health. About 96.7% of the human body is composed of 4 elements - oxygen (O), carbon (C), hydrogen (H), and nitrogen (N) - and the remaining is composed of minerals.
Practice : Dentistry
Keywords : Metal Allergy, Patch Test, Toxic Metals, Hair mineral analysis, Mercury