アブストラクト（38巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Dispersion of Hydrophobic Monomers in Cytotoxic Test Medium
Subtitle　：
Authors　： Shigeaki Kurata1), Kozo Umemoto1), Kumiko Morisita1), Kazuo Shimoyama1), Toshio Kawase2)
Authors（kana）　：
Organization　： 1)Department of Biomaterials and Devices, Kanagawa Dental College, 2)Department of Dental Biomaterials and Bioengineering, Kanagawa Dental Collage
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 38
Number　： 2
Page　： 63-66
Year/Month　： 2010 / 9
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] The dispersion of hydrophobic monomers, such as methyl methacrylate (MMA) and 2,2-bis[4-(2-hydroxy-3-methacryloyloxypropyl phenyl)propane] (BisGMA) in a medium was analyzed with high performance liquid chromatography. The concentration of MMA in the medium was gradually reduced over nine hours to an infinitesimal quantity both with and without 1 mass% dimethyl sulfoxide in the media. On the other hand, the concentration of BisGMA in the upper fraction of the medium was higher than that of the lower. These facts showed that the MMA and BisGMA in the medium were not homogeneously dispersed and that the cytotoxic test could not be relied upon to give a correct evaluation. However, there was no difference in the concentration of TEGDMA between the upper and lower fractions of the medium, because, in contrast with BisGMA, TEGDMA is a hydrophilic compound.
Practice　： Dentistry
Keywords　： Cytotoxic test, Hydrophobic monomer, Dispersion