アブストラクト（38巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Determination of serum BRAK / CXCL14 level in healthy volunteers
Subtitle　： Selective Proceedings of 44th General Meeting of Kanagawa Odontological Society, 2009
Authors　： Kazuhito Izukuri1),2), Shin Ito1),2), Naohito Nozaki2),1), Nobuyuki Yajima1),2), Mariko Iwamiya3), Sachiko Kawahara1),2), Kenji Suzuki1),4), Eriko Kubota1),4), Ryu-Ichiro Hata1),2)
Authors（kana）　：
Organization　： 1)Oral Health Science Research Center, 2)Department of Biochemistry and Molecular Biology, 3)Clinical Laboratory, 4)Department of Maxillofacial Surgery, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 38
Number　： 2
Page　： 101-103
Year/Month　： 2010 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [ABSTRACT] BRAK/CXCL14 is a chemokine that is expressed in many normal cells and tissues. Several papers have reported tissue distribution, but no study has examined the serum protein level of this chemokine. We evaluated serum levels of BRAK/CXCL14 by enzyme-linked immunosorbent assay, after having determined the conditions necessary to increase the sensitivity and reproducibility of the method. The average level of males was significantly higher than that of females. Two percent of the volunteers showed a value 2 S.D. higher than the average value without any obvious abnormality, but no person was lower than 1 S.D. of the average value. The serum BRAK/CXCL14 levels of individual subjects were quite constant. These data indicate that the serum BRAK/CXCL14 level is highly conserved and suggest that the levels are determined by genetic background and/or life style of the individual.
Practice　： Dentistry
Keywords　： Chemokine, B RAK/CXCL14, enzyme-linked immunosorbent assay(ELISA)