アブストラクト（52巻1/2号：神奈川歯学）

神奈川歯学

Japanese

Title　： 下顎骨に発生した正角化性歯原性嚢胞の2例
Subtitle　： 症例
Authors　： 岩瀬博建*,**, 石川美香*, 加藤洋史*, 佐々木忠昭*
Authors（kana）　：
Organization　： *社会医療法人中山会宇都宮記念病院歯科口腔外科, **いわせ歯科口腔外科耳鼻咽喉科クリニック
Journal　： 神奈川歯学
Volume　： 52
Number　： 1/2
Page　： 31-39
Year/Month　： 2017 / 12
Article　： 報告
Publisher　： 神奈川歯科大学学会
Abstract　： 「緒言」 1956年にPhilipsenによって歯原性角化嚢胞(Odontogenic keratocyst: OKC)が命名されたが, その生物学的態度について種々の議論があった. このため, 2005年のWHO分類では, 今までOKCと分類されていた中で, 裏層上皮が錯角化を示すものが角化嚢胞性歯原性腫瘍(Keratocystic odontogenic tumor: KCOT)として新しく歯原性腫瘍に分類された. 一方, OKCで裏層上皮が正角化を示す正角化性歯原性嚢胞(Orthokeratinaized odontogenic cyst: OOC)については詳細な記載がなく, AFIP (Armed Forces Institute of Pathology)の分類で項目が記載されたのみである. ところが, 2017年のWHO歯原性腫瘍新分類では, OKCとは独立した疾患としてOOCが新たに嚢胞性疾患として記載された. 今回, われわれは下顎骨に発生した比較的まれなOOCの2例を経験したので報告する.
Practice　： 歯科学
Keywords　： 正角化性歯原性嚢胞 (OOC), 症例報告, 2017年WHO歯原性腫瘍新分類

English

Title　： Orthokeratinized Odontogenic Cyst of the Mandible : A Report of Two Cases and Review of the Literature
Subtitle　：
Authors　： Hirotate IWASE*,**, Mika ISHIKAWA*, Hiroshi KATO*, Tadaaki SASAKI*
Authors（kana）　：
Organization　： *Department of Oral and Maxillofacial Surgery, Utsunomiya Memorial Hospital, **Iwase Dental, Oral Surgery and Otolaryngology Clinic
Journal　： Kanagawa Shigaku
Volume　： 52
Number　： 1/2
Page　： 31-39
Year/Month　： 2017 / 12
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] The orthokeratinized odontogenic cyst (OOC) is a relatively rare developmental odontogenic cyst of the jaws that occurs predominantly in males between the third and fourth decades. The OOC was described in 1981 as a variant of odontogenic keratocyst and was not included in previous editions of the WHO classification. According to the 2017 World Health Organization classification of odontogenic tumours, OOC has now finally classified as a distinct entity. In this report, we presented two cases of OOC. Case 1. A 32-year-old female was referred presenting bleeding and bad smell from the gingiva of the right mandible. The panoramic radiograph revealed a well-defined radiolucency existing from the right mandibular body to ascending ramus. Based on the biopsy, the histopathological diagnosis was OOC. The extraction of the 4.8 and the nucleation of the lesion were made under general anesthesia. After eight months of follow-up, no sign of recurrence has been noted. Case 2. A 35-year-old female was referred to our department because of a pointed out the boundary clear unilocular transmission image of the left mandibular body at the X-ray examination in the near dental clinic. The clinical diagnosis of the mandibular cyst was made and the extraction of the 4.8 and enucleation of the lesion were performed under general anesthesia. The histopathological diagnosis was OOC. The outcome was favorable, and after four months, no signs of recurrence have been recognized. In addition to histopathological examination, immunohistochemical detection was performed using antibodies against podoplanin, bcl-2, and CK19. The purpose of this article is not only to present two cases of OOC arising in the mandible but also to review the literature on OOC.
Practice　： Dentistry
Keywords　：