アブストラクト(8巻2号:神奈川歯学)

神奈川歯学

Japanese

Title : Papillary cystadenoma lymphomatosum (Warthin腫) の臨床病理学的検討
Subtitle : 原著
Authors : 長井好子, 小園知, 久田太郎
Authors(kana) :
Organization : 神奈川歯科大学病理学教室
Journal : 神奈川歯学
Volume : 8
Number : 2
Page : 47-58
Year/Month : 1973 / 10
Article : 原著
Publisher : 神奈川歯科大学学会
Abstract : 「抄録」 当病理学教室で経験した8例のWarthin腫瘍について臨床的, 病理組織学的検索を行い, 更に自験例を中心に文献的考察を加えて報告した. 本腫瘍は48~70才の中年以後に認められ, 性別は一般的に男性に多いが, 自験例では男女同数であった. 発生部位は耳下腺部5例, 顎下腺部3例で, 顎下腺部の発生が注目された. 腫瘤の大きさは, 示指頭大から鵞卵大を示し, 病悩期間は1ヵ月より20年に及ぶ. 再発, 悪性化は現在のところみられない. 組織学的には全例に上皮成分のoncocyte化を認めたが, この所見は一次的な意義を有する所見ではなく, むしろ二次的変化と理解された. 比較的若年者(48才)で病悩期間の短い症例に於いて, 上皮成分の粘液細胞化ないしGoblet cellを多数認め, 同時に線毛を電子顕微鏡的に証明した. この事は本腫瘍の初期像乃至原型を示唆するものと考える. 又, 基質に相当する部位のリンパ組織に於いて8例中7例に明瞭な明中心を認め, 同時に形質細胞の浸潤が著明であったが, 免疫との関係は臨床検査等に於いて尚明らかでない. 更に組織発生について若干の考察を加えた.
Practice : 歯科学
Keywords :

English

Title : Clinicopathological study of Papillary Cystadenoma Lymphomatosum (Warthin's tumor)
Subtitle :
Authors : Y.Nagai, S.Ozono, T.Hisada
Authors(kana) :
Organization : Dept. of Pathology, Kanagawa Dental College
Journal : Kanagawa Shigaku
Volume : 8
Number : 2
Page : 47-58
Year/Month : 1973 / 10
Article : Original article
Publisher : Kanagawa Odontological Society
Abstract : Eight cases of Warthin's tumor experienced in our department of pathology were studied clinically and histopathologically. The results were sammarized in the following items from 1) to 10). Our cases were discussed with reference to the cases on literatures. 1) Age distribution ranged from 48 to 70 years old showing frequent occurence above the middle aged. 2) Warthin's tumor developed in the region of the parotid gland in 5 cases, and in the submandibular region in 3 cases; the development in the region of the submandibular gland was significant. 3) The masses ranged from the size of the head of the index finger to that of duck egg. 4) The period of disease ranged 1 month to 20 years. 5) No recurrence of malignant changes were noted so far. 6) Histological examination revealed oncocytic metaplasia of the epitherial cells in all the cases, which considered to bo secondary changes, not the primary changes. 7) Rather young patient, 48 years old, having short period of development showed frequent mucous change and Goblet cells in the epithelial cells, which also demonstrated cillia on electron microscopic examination. 8) Lymphoid tissue infiltrating into the stroma showed difined germinal center in 7 of the 8 cases, and plasma cell infiltration was also remarkable. 9) The histogenesis was discussed.
Practice : Dentistry
Keywords :