アブストラクト(16巻4号:神奈川歯学)

神奈川歯学

Japanese

Title : 口腔領域が関係した重複癌の2症例と統計的観察
Subtitle : 症例
Authors : 近藤功*, 清水洋子*, 三木慎一郎*, 片瀬秀士*, 渋谷大陸*, 秦順一**, 笹平秀一**
Authors(kana) :
Organization : *神奈川歯科大学病理学教室, **東海大学医学部病理学教室
Journal : 神奈川歯学
Volume : 16
Number : 4
Page : 571-584
Year/Month : 1982 / 3
Article : 報告
Publisher : 神奈川歯科大学学会
Abstract : 「緒言」 1879年Billrothが初めて原発性重複悪性腫瘍の症例を報告し, 定義づけをして以来, 現在まで多くの重複癌に関する症例報告, 統計的検索が加えられている. Billrothのいう重複癌(multiple primary malignant tumors)は, 1) 重複癌を構成する各腫瘍は互いに異なる組織像を呈し, 2) 各腫瘍はそれぞれ異なる母組織から発生し, 3) 各腫瘍は別々の転移巣をもつ. と定義されている. しかし, この定義は厳格すぎるのと, 不必要なものも含まれているため, 1932年Warren and Gatesはこの定義を修正し, 重複癌を次のように規定した. 1) 重複癌を構成する各腫瘍は悪性像を呈し, 2) 各腫瘍は互いに離れた部位を占め, 3) 一方の腫瘍が他方の転移でないことを証明できること. 今日ではこのWarren and Gatesの定義が広く用いられている. さらに赤崎らはこれに加え, 同一臓器において2つ以上の悪性腫瘍が独立的に発生した場合も重複癌とし, その枠付けを広くとっている.
Practice : 歯科学
Keywords :

English

Title : Multiple Primary Malignant Tumors Associated with an Oral Region - Case Report and Statistical Observation -
Subtitle :
Authors : Isao KONDO*, Yoko SHIMIZU*, Shinichiro MIKI*, Hideshi KATASE*, Hiromitsu SHIBUYA*, Junichi HATA**, Shuichi SASADAIRA**
Authors(kana) :
Organization : *Department of Pathology, Kanagawa Dental College, **Department of Pathology, Tokai University School of Medicine
Journal : Kanagawa Shigaku
Volume : 16
Number : 4
Page : 571-584
Year/Month : 1982 / 3
Article : Report
Publisher : Kanagawa Odontological Society
Abstract : Abstract : The multiple primary malignant tumors were first reported by Billroth in 1869. We had an experience with two patients with multiple primary malignant tumors. The first case was 40 year old female who had carcinoma in the maxilla and thyroid, the second case was 64 year old male who had carcinoma in tongue and esophagus. To find out the incidence of multile primary malignant tumors associated with an oral region, a statistical survey was conducted on a total 3283 oral malignant tumor cases, which were listed in the Annual of the Pathological Autopsy Cases in Japan from 1969 to 1978. There is a tendecy of the rate of such cases to increase year by year. 1) Multiple primary malignant tumors were found in 206 cases or 6.3% of the total. Of special interest was the unusually frequent occurrence of multiple primary malignant tumors involing the tongue cancer - a rate of occurrance of 9.8%. 2) Out of 206 cases, 157 cases occured in male and 49 cases female (3.2 : 1), 130 (63%) cases occured at the age of 60-79. 3) As to the primary site in the oral region, the pharynx came on top the list (27.1%). Runners up were tongue, maxilla (each 25.2%), oral floor (5.8%). 4) The lagest number of other organs involved was gastric cancer (52.8%). They were as follows : stomach 50 (21.8), ; esophagus 28 (12.2), ; lung 21 (9.2%). 5) Out of 206 cases, there were 23 cases of triple malignant tumors. The oral site involved were as follows : pharynx 8, ; tongue 6, ; maxilla 3, and the othr organ involved were as follows : stomach 5, ; esophagus 4, ; colon 4, ; kidney 3.
Practice : Dentistry
Keywords :