アブストラクト(22巻3号:神奈川歯学)

神奈川歯学

Japanese

Title : 骨シンチグラフィーとゼロラジオグラフィーを用いた骨傷治癒過程に関する基礎的研究
Subtitle : 原著
Authors : 佐藤和夫1),2), 五十嵐清治1), 金子昌幸2)
Authors(kana) :
Organization : 1)東日本学園大学歯学部小児歯科学講座, 2)東日本学園大学歯学部歯科放射線学講座
Journal : 神奈川歯学
Volume : 22
Number : 3
Page : 490-505
Year/Month : 1987 / 12
Article : 原著
Publisher : 神奈川歯科大学学会
Abstract : 「はじめに」骨傷治癒過程に関する研究の歴史は古く, これまでに多数の報告が成されてきた. 観察の方法や対象も多岐にわたり, 研究者の目的によって最も適するものが選ばれてきたことは当然のことと考えられる. 多くはX線学的観察と病理学的観察が中心を成してきたが, 近年では, 放射性同位元素やマイクロラジオグラフィーなどの新しい手法を用いたものも少なくはない. しかし, 放射性同位元素の利用といっても, ラットやマウス等の小型動物による実験的研究では, その利用方法も, オートラジオグラフィーや放射能摂取量の測定などに限られていたのが現状である. これまでに, 小型動物の骨傷治癒過程, 特に, 顎骨の骨傷治癒過程の観察に, 骨シンチグラフィーが利用されたとの報告は極めて少ない. 小型実験動物の骨シンチグラフィーに適した撮像装置が存在しなかったことが最大の原因として挙げられる. しかし近年になり, 長田らや金子らによって, ラットやマウスの骨シンチグラフィーが可能となるシンチレーションスキャナーやガンマーカメラの改良が成されてきた.
Practice : 歯科学
Keywords : 骨シンチグラフィー, ゼロラジオグラフィー, 骨傷治癒過程

English

Title : Fundamental Study on the Healing of Bone Injuries with Bone Scintigraphy and Xeroradiography
Subtitle :
Authors : Kazuo SATOH1),2), Seiji Igarashi1), Masayuki Kaneko2)
Authors(kana) :
Organization : 1)Department of Pedodontics, Higashi Nippon Gakuen University, School of Dentistry, 2)Department of Dental Radiology, Higashi Nippon Gakuen University, School of Dentistry
Journal : Kanagawa Shigaku
Volume : 22
Number : 3
Page : 490-505
Year/Month : 1987 / 12
Article : Original article
Publisher : Kanagawa Odontological Society
Abstract : [Abstract]: The healing process of bone injuries in the rat mandiblae was examined with bone scintigraphy, soft X-ray radiography, xeroradiography and microradiography. Fifty rats of about 200g were offered to this study and fractures were experimentally produced in the left mandiblae. Five of them were examined with bone scintigraphy using a pinhole collimeter improved by Kaneko and his co-workers, and the others were examined with soft X-ray radiography, xeroradiography and microradiography. These radiological observations were carried out immediately, 4 days, 7 days, 14 days, 28 days, 35 days, 42 days and 49 days after fracturing. Histological examinations, in addition, were made to evaluate the relationships between the findings. The bone scintigrams obtained on the 4th day showed a slight uptake of 99mTc, although no noteworthy findings were demonstrated on the soft X-ray radiograms and xeroradiograms. The uptake of 99mTc was gradually increased. The most remarkable accumulation was seen on the 21st day after fracturing. The bone scintigrams obtained on the 49th day showed as same images as were obtained from the normal rats. Soft X-ray radiograms and xeroradrograms demonstrated no changes in radiolucency until the 4th day after fracturing, although the bone scintigrams revealed an uptake of 99mTc. The radiopacity was gradually increased until the 49th day. Microradiograms obtained on the 4th day revealed some early changes, which appeared on the periosteal regions. New callus formation was observed from the 7th day after fracturing. The calcification of new callus was gradually increased until the 49th days. Histological findings obtained on the each stages supported these findings.
Practice : Dentistry
Keywords :