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アブストラクト（24巻4号：神奈川歯学）
Japanese
| Title ： | 乳歯歯質の微量金属に関する研究 -出生前および出生後形成歯質における微量金属含有量について- |
|---|---|
| Subtitle ： | 原著 |
| Authors ： | 丹下貴司*1, 檜垣旺夫*1, 斎藤滋*2 |
| Authors（kana） ： | |
| Organization ： | *1神奈川歯科大学小児歯科学教室, *2神奈川歯科大学口腔生化学教室 |
| Journal ： | 神奈川歯学 |
| Volume ： | 24 |
| Number ： | 4 |
| Page ： | 653-670 |
| Year/Month ： | 1990 / 3 |
| Article ： | 原著 |
| Publisher ： | 神奈川歯科大学学会 |
| Abstract ： | 「緒言」 近年, フロンガスによるオゾン層の破壊や大気中CO2の増加による温暖化現象など環境問題がにわかにクローズアップされてきている. 同時に産業の工業化に伴い, 環境中に存在する微量金属の生態系に与える影響も注目を集めている. 微量金属の生体における生理学的機能および毒性については多くの研究が報告されており, Zn, Cuのような必須微量金属に関しては, 生体内酵素活性との関わり合いや栄養学的な見地から過不足に伴う生体機能・成長発育の変化についての研究が, 一方ではCd, Pbのような非必須と考えられる重金属についても, 水俣病やイタイイタイ病に代表されるような人為的環境汚染の問題から, 主として過剰症状についての研究が進められている. 歯科領域においても環境汚染との問題, 齲蝕との関連, 歯質形成・石灰化過程との関連など多岐にわたる分野で従来より多くの報告がみられる. 乳歯の形成は胎生期から小児期に至る長期間にわたり行われ, さらに一度形成された歯はほとんど生理的交代(turn over)に乏しいために, 歯質形成途上で生じる局所的ならびに全身的影響を歯質内部に刻印づけたまま存在するという特性を有する. |
| Practice ： | 歯科学 |
| Keywords ： | 微量金属, 乳歯, 新産線, 出生前, 出生後 |
English
| Title ： | A Study of Trace Elements in Deciduous Teeth -The Differences of Cd, Zn, Pb, and Levels in Prenatally and Postnatally Formed Deciduous Teeth- |
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| Subtitle ： | |
| Authors ： | Takashi TANGE*1,*2, Morio Higaki*1, Shigeru Saito*2 |
| Authors（kana） ： | |
| Organization ： | *1Department of Pediatric dentistry, Kanagawa Dental Collge, *2Department of Oral Biochemistry, Kanagawa Dental College |
| Journal ： | Kanagawa Shigaku |
| Volume ： | 24 |
| Number ： | 4 |
| Page ： | 653-670 |
| Year/Month ： | 1990 / 3 |
| Article ： | Original article |
| Publisher ： | Kanagawa Odontological Society |
| Abstract ： | [Abstract]: It has been reported by some investigators that deciduous teeth could be useful materials for the analysis of the trace elements available to the human body burden. In this study, an attempt was made to define that uptake of trace elements (Cd, Zn, Pb and Cu) take place during formation of the deciduous tooth. Samples were prepared from exfoliated human upper deciduous central incisors devided into two or three sections at incremental lines includes neonatal line. Samples were dissolved with nitric acid and dried at 80℃. Each element was separated chromatographically using aceton-HCl gradient solution with a cation exchange resin and then analyzed by flameless atomic absorption spectrophotometry. The results were as follows : 1. Ca, P, Ca/P ratio levels showed no significant differences between prenatally and postnatally formed teeth. 2. In the enamel, (1) Cd level showed a tendency to be higher in the postnatally formed enamel, but not significant. (2) Zn and Pb levels were found to be significantly higher in the postnatally formed than in the prenatally formed enamel. (3) Cu level was reversed significantly. 3. In the dentin, (1) Cd and Cu levels in the postnatally formed dentin I were significantly less than prenatally formed denin, and these were almost equal to the postnatally formed dentin II. (2) Zn level in the postnatally formed dentin I was almost equal to the prenatally formed dentin, but that was significantly less than the postnatally formed dentin II. (3) Pb level in the postnatally formed dentin I was significantly less than the prenatally formed dentin and the postnatally formed dentin II. Therefore, the results suggest that the accumulation of Cd and Cu to the deciduous tooth mainly occur in the prenatal and the accumulation of Zn and Pb to the deciduous tooth occur not only in the prenatal but also continuously in the postnatal, and the deciduous tooth can be a useful materials for environmental contamination recorder. |
| Practice ： | Dentistry |
| Keywords ： |
