アブストラクト(29巻4号:神奈川歯学)

神奈川歯学

Japanese

Title : 人工骨移植後の歯周組織再生に関する研究 第2報 : 吸収性材料Tricalcium phosphate (TCP) 移植後の血管および骨変化について
Subtitle : 原著
Authors : 渕田恒晴*, 菅谷彰*, 松尾雅斗**, 堀俊雄*, 高橋和人**
Authors(kana) :
Organization : *神奈川歯科大学歯科保存学教室第II講座, **神奈川歯科大学口腔解剖学教室
Journal : 神奈川歯学
Volume : 29
Number : 4
Page : 309-323
Year/Month : 1995 / 3
Article : 原著
Publisher : 神奈川歯科大学学会
Abstract : 「緒言」 歯周疾患により失われた歯周組織の回復を図るため骨移植法や, GTR法など, 生体材料を使用した歯槽骨再建療法が行われている. このような人工骨移植材を材料と周囲組織の関係から分類すると 1) 生体許容性材biotolerant material 骨組織と移植材の間に厚い線維組織が形成され, 骨とは直接接合しないもの(bone cement, stainless steel) 2) 生体不活性材bioinert material 骨組織と移植材の間に薄い線維組織が形成され, 骨と接合する場合がある(carbon material, alumina) 3) 生体活性材bioactive material 骨と移植材が化学的に結合する(bioglass, hydroxyapatite) 4) 生体内崩壊材biodegradable material 組織内において崩壊し, 新性骨と置換する(tricalucium phosphate, 低結晶のhydroxyapatite)ものに分類される.
Practice : 歯科学
Keywords : 歯周組織, TCP, 血管鋳型法, 走査型電子顕微鏡

English

Title : The Study of Regenerating Process after Implanation of Tricalcium Phosphate (TCP) II. Changes of Vascular Architecture and Bone Remodeling in Periodontal Tissue using Resin Cast Method
Subtitle : Original article
Authors : Tsuneharu FUCHIDA*, Akira SUGAYA*, Masato MATSUO**, Toshio Hori*, Kazuto Takahashi**
Authors(kana) :
Organization : *Department of Periodontology, Kanagawa Dental College, **Department of Oral Anatomy, Kanagawa Dental College
Journal : Kanagawa Shigaku
Volume : 29
Number : 4
Page : 309-323
Year/Month : 1995 / 3
Article : Original article
Publisher : Kanagawa Odontological Society
Abstract : Abstract : Tricalcium phosphate (TCP) granules was implanted in artificially created periodontal bone defects (Artificial bone defect). After seven, 30 and 90 days, animals were sacrificed, then vascular corrosive resin cast method, scanning electolon microscopy and histological observation using India ink injection method were done. (Experimental protocol was same as previous report of HAP implant) The results were as follows ; 1) After 7 days, Artificial bone defect was filled by TCP and newly formed blood vessels was observed. New bone formation showed only the bottom regions in the Artificial bone defect. 2) 30 weeks later, TCP and newly formed bone include many blood vessels filled in the Artificial bone defect. Connection of TCP granules and new bone was not tightly compare to HAP, Owing to existence of vascular which played to resolve the granules and form the bone. 3) 90 days later, bone trabecular pattern was formed in the Artificial bone defect where had many blood vessels and TCP granules, but these granules were smaller than before periods. We conclude the TCP make new bone formation by osteoconduction, and the character of TCP degradation is implicate the tissue remodeling which is materials resorption and bone formation, rather than osteoconduction.
Practice : Dentistry
Keywords : TCP