アブストラクト（53巻1/2号：神奈川歯学）

神奈川歯学

English

Title　： A SEM study on microvascular changes in a lifestyle-related disease
Subtitle　： Mini Review
Authors　： Masato MATSUO, Masahiro TO, Satoko WADA-TAKAHASHI, Shun-suke TAKAHASHI
Authors（kana）　：
Organization　： Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University
Journal　： Kanagawa Shigaku
Volume　： 53
Number　： 1/2
Page　： 37-39
Year/Month　： 2018 / 12
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] In this study, we focus on the microcirculation of whole and oral organs in a lifestyle-related disease. In the microvascular resin cast method, low-viscosity synthetic resin is injected into the blood vessels and the peripheral tissue is dissolved, revealing all of the blood vessels. A clear three-dimensional image can be obtained through the complete infusion of a synthetic resin up to the capillaries, and these can be observed using a scanning electron microscope (SEM) with deep focus. Moreover, the intravascular surface structures of endothelial cells and their nuclei and venous valves are imprinted accurately on the surface of the cast. The diameter of the cast allows the microcirculatory system to be distinguished from the arteries through the arterioles and capillaries to the venules and veins. In this study, we prepared vascular casts using a rat model of diabetes and compared the three-dimensional structures of vessels in control and diabetic rats.
Practice　： Dentistry
Keywords　： Microcirculation, Lifestyle-related diseases, Vascular resin-cast, SEM