アブストラクト（53巻1/2号：神奈川歯学）

神奈川歯学

English

Title　： The bactericidal and antioxidant effects of cacao bean extracts against periodontal pathogen
Subtitle　： Mini Review
Authors　： Haruka SASAKI1), Ayaka YOSHIDA2), Fumihiko YOSHINO2), Keitaro INABA1), Takenori SATO3), Hiroko HIRAMINE4), Kiyoko WATANABE1), Nobushiro HAMADA1)
Authors（kana）　：
Organization　： 1)Division of Microbiology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 2)Division of Photomedical Dentistry, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 3)Division of Oral Molecular and Cellular Biochemistry, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 4)Department of Highly Advanced Stomatology, Graduate School of Dentistry, Kanagawa Dental University
Journal　： Kanagawa Shigaku
Volume　： 53
Number　： 1/2
Page　： 45-48
Year/Month　： 2018 / 12
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Cacao beans extract is a polyphenol containing the favorite food such as chocolates. In this mini review, we focused on the bactericidal and antioxidant effects of cacao bean extracts against Porphyromonas gingivalis. Cacao bean extracts in this study were used cacao bean polyphenol-rich extract (CBP) and HP cacao extract (PW-VE-R). To determine the bactericidal effects of cacao bean extracts, assessed the improvement effects on periodontal disease using two types of cacao bean extracts against P. gingivalis. The bactericidal effect of CBP was stronger than that of PW-VE-R against P. gingivalis cells. These extracts were decreased P. gingivalis biofilm in a dose-dependent manner. In addition, the scavenging activities against the reactive oxygen species such as superoxide and hydroxyl radical were indicated with cacao bean extract. Electron Spin Resonance analysis revealed that the two types of cacao bean extracts have scavenged the reactive oxygen species such as hydroxyl radicals and superoxide. These results suggested that cacao bean extracts might improvement effects on periodontal tissue destruction.
Practice　： Dentistry
Keywords　： Cacao bean extract, Periodontal disease, Porphyromonas gingivalis, Reactive oxygen species