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アブストラクト（53巻1/2号：神奈川歯学）
English
| Title ： | Effects of dyslipidemia on blood and saliva components in rats |
|---|---|
| Subtitle ： | Mini Review |
| Authors ： | Masahiro TO, Juri SARUTA, Nobuhisa KUBOTA, Keiichi TSUKINOKI |
| Authors（kana） ： | |
| Organization ： | Department of Oral Science, Graduate School of Dentistry and Kanagawa Dental University, Yokosuka |
| Journal ： | Kanagawa Shigaku |
| Volume ： | 53 |
| Number ： | 1/2 |
| Page ： | 49-51 |
| Year/Month ： | 2018 / 12 |
| Article ： | Report |
| Publisher ： | Kanagawa Odontological Society |
| Abstract ： | [Abstract] Saliva testing provides considerable information and is noninvasive. Although dyslipidemia alters blood components, its effects on saliva remain unclear. We investigated these changes using a dyslipidemia rat model. Three-week-old male rats were fed with high-fat or control diet for 10 weeks. Blood, saliva, salivary gland, and liver were collected for histological and biochemical analyses. We showed that dyslipidemia causes fatty liver and increases levels of triglycerides and brain-derived neurotrophic factor (BDNF) in blood and saliva, suggesting BDNF regulates lipid metabolism. |
| Practice ： | Dentistry |
| Keywords ： | Dyslipidemia, BDNF, Saliva, Blood |
