アブストラクト（53巻1/2号：神奈川歯学）

神奈川歯学

English

Title　： Potential use of antimicrobial photodynamic therapy in dentistry
Subtitle　： Mini Review
Authors　： Ayaka YOSHIDA1), Haruka SASAKI2), Yukako SHIOTSU-OGURA1), Kazuhito IZUKURI3), Nobushiro HAMADA2), Fumihiko YOSHINO1)
Authors（kana）　：
Organization　： 1)Division of Photomedical Dentistry, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 2)Division of Microbiology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 3)Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University
Journal　： Kanagawa Shigaku
Volume　： 53
Number　： 1/2
Page　： 60-62
Year/Month　： 2018 / 12
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] After antibiotics were discovered as a method of sterilization microorganisms, the interest of people has been diminished from the research and application of photodynamic sterilization method. However, the necessity for the innovative antimicrobial strategies instead of the conventional antibiotics have required, because the speed of microbial antibiotic resistance acquisition is recently to be on the increase. Therefore, the photodynamic therapy has been paid attention again. Also, antibacterial photodynamic therapy (aPDT) is starting to be applied to the periodontal treatment in the dental field. However, the main evidences of aPDT in dentistry are the clinical reports by practitioner, therefore, little consideration is given to the sterilization mechanism and safety for the body. In this review, we introduce that background of aPDT and our report of the examination of bactericidal mechanism of aPDT applying periodontal bacterial pigment and its sterilizing capacity.
Practice　： Dentistry
Keywords　： Porphyromonas gingivalis, Blue light, Antimicrobial photodynamic therapy, Protoporphyrin IX